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Reverse transcriptase activity in psoriatic lesions: effects of reverse transcriptase inhibitors on keratinocyte proliferation and differentiation

✍ Scribed by Jean-Pierre Molès, Anne Tesniere, Marc Dumas, Frédéric Bonté, J-J Guilhou

Book ID: 120692071
Publisher: BioMed Central
Year: 2009
Tongue: English
Weight: 66 KB
Volume: 6
Category: Article
ISSN: 1742-4690
DOI: 10.1186/1742-4690-6-S2-P60

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## Abstract Normal somatic cells possess a finite life span owing to replicative senescence. Telomerase functions as a potential regulator of senescence in various cells. Expression level of human telomerase reverse transcriptase (hTERT) is correlated with telomerase activity and cellular immortali