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Reverse immunology approach for the identification of CD8 T-cell-defined antigens: Advantages and hurdles

✍ Scribed by VIATTE, SEBASTIEN; ALVES, PEDRO M; ROMERO, PEDRO


Book ID
108944584
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
201 KB
Volume
84
Category
Article
ISSN
0818-9641

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## Abstract CD8+T lymphocytes activated in peripheral lymphoid organs are believed to preferentially localize to the hepatic sinusoids, but the role of antigen in the process has been difficult to define. To create experimental mice in which the liver was unique in lacking the ability to present an