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Reversal of the reserpine-induced depletion of brain serotonin by a monoamine oxidase inhibitor

✍ Scribed by N. Canal; A. Maffei-Faccioli

Book ID
111164507
Publisher
John Wiley and Sons
Year
1959
Tongue
English
Weight
99 KB
Volume
5
Category
Article
ISSN
0022-3042

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## Abstract The effect of a lack of the gene encoding monoamine oxidase A (MAO A) in transgenic Tg8 mice on the activity of tryptophan hydroxylase (TPH), the rate‐limiting enzyme in serotonin (5‐HT) biosynthesis, and on the levels of 5‐HT and 5‐hydroxyindoleacetic acid (5‐HIAA) in the midbrain, hyp