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Reversal of Synaptic Memory by Ca2+/Calmodulin-Dependent Protein Kinase II Inhibitor

✍ Scribed by Sanhueza, M.; McIntyre, C. C.; Lisman, J. E.


Book ID
118747025
Publisher
Society for Neuroscience
Year
2007
Tongue
English
Weight
427 KB
Volume
27
Category
Article
ISSN
0270-6474

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## Abstract Hippocampal α‐calcium/calmodulin‐dependent protein kinase II (Ξ±CaMKII) has been implicated in neuronal plasticity and spatial learning. In the present experiment, an adeno‐associated virus (AAV) vector was designed to express Ξ±CaMKII driven by the U6 promotor. Microinfusion of this vect