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Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR

✍ Scribed by Michiel de Bruin; Keisuke Miyake; Thomas Litman; Robert Robey; Susan E. Bates


Book ID
117469544
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
179 KB
Volume
146
Category
Article
ISSN
0304-3835

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## Abstract Head and neck cancers are treated by a combination of surgery, radiotherapy and/or chemotherapy. The clinical success of cisplatin‐based chemotherapy, mostly in combination with 5‐FU or a taxane, is however limited by multifactorial intrinsic or acquired resistance. So far, known genes