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Reversal of P-glycoprotein expressed in Escherichia coli leaky mutant by ascorbic acid

โœ Scribed by Eman M El-Masry; Mohamed B Abou-Donia

Book ID
117174176
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
375 KB
Volume
73
Category
Article
ISSN
0024-3205

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Deficiency of propionyl-CoA carboxylase (PCC) results in propionic acidemia, an autosomal recessive disorder characterized by ketoacidosis sufficiently severe to cause neonatal death. PCC is involved in the catabolism of branched-chain amino acids, odd-chain fatty acids, and cholesterol. The enzyme