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Reversal of Natural Killing Susceptibility in Target Cells Expressing Transfected Class I HLA Genes

✍ Scribed by Walter J. Storkus, Jeff Alexander, J. Alan Payne, Jeffrey R. Dawson and Peter Cresswell


Book ID
123636699
Publisher
National Academy of Sciences
Year
1989
Tongue
English
Weight
745 KB
Volume
86
Category
Article
ISSN
0027-8424

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HLA class I antigens of the human major histocompatibility complex (MHC) play an important role in immune response. Consistent with their role in immune surveillance, these antigens are expressed on most cell types. However, a marked deficiency or lack of expression of these antigens has been observ