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Reversal of histamine-mediated immunosuppression by structurally diverse histamine type II (H2) receptor antagonists

โœ Scribed by Alison M. Badger; Jean Young; George Poste


Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
457 KB
Volume
6
Category
Article
ISSN
0192-0561

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Stimulation of central histamine H, and or H, receptors with histaminergic drugs results in a dose-related pressor response and bradycardia in conscious, freely-moving rats. Two recently developed peripheral histamine H, antagonists, MK-208 and BMY-26368, as well as cimetidine, were evaluated with r