Morphological changes in muscle tissue o
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LΓ©on P. F. Winkel; Joep H. J. Kamphoven; Hannerieke J. M. P. Van Den Hout; Lies
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Article
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2003
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John Wiley and Sons
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English
β 621 KB
## Abstract Pompe's disease (glycogen storage disease type II) is an autosomal recessive myopathy caused by lysosomal Ξ±βglucosidase deficiency. Enzyme replacement therapy (ERT) is currently under development for this disease. We evaluated the morphological changes in muscle tissue of four children