Reversal of acute apparent diffusion coefficient abnormalities and delayed neuronal death following transient focal cerebral ischemia in rats

Separating changes in the intra- and ext

Separating changes in the intra- and extracellular water apparent diffusion coefficient following focal cerebral ischemia in the rat brain

✍ Matthew D. Silva; Tsuyoshi Omae; Karl G. Helmer; Fuhai Li; Marc Fisher; Christop 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 375 KB

## Abstract Selective intracellular (IC) and extracellular (EC) brain water apparent diffusion coefficient (ADC) values were measured in normal and ischemic rat brain. Selective __T__~1~‐relaxation enhancement of the EC water, using intracerebroventricular (ICV) infusion of an NMR contrast reagent