Retroviral transfer of HSV1-TK gene into
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Y. Hasegawa; N. Emi; K. Shimokata
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Article
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1995
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Springer
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English
⚖ 603 KB
We used a recombinant retrovirus as one of the potential vectors for human gene therapy to transfer a drug sensitivity gene into human lung cancer cells. The gene encoding the thymidine kinase (TK) of herpes simplex virus type 1 (HSVI) was used as the drug sensitivity gene. The antiherpes drugs acyc