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Retrospectives and perspectives on the biological activity of histidine-containing dipeptides

✍ Scribed by A.A. Boldyrev


Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
479 KB
Volume
22
Category
Article
ISSN
0020-711X

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2-adamantanole was the protecting group of the aspartate 13-COOH moiety during the peptide synthesis and survived the final peptide cleavage and deprotection carried out under controlled conditions. MEN 10586 showed an agonist activity comparable to that of the parent compound MEN 10210 at NK~ and N