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Retrospective, longitudinal analysis of serum human herpesvirus-8 viral DNA load in AIDS-related kaposi's sarcoma patients before and after diagnosis

✍ Scribed by Abeltje M. Polstra; Marion Cornelissen; Jaap Goudsmit; Antoinette C. van der Kuyl


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
121 KB
Volume
74
Category
Article
ISSN
0146-6615

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✦ Synopsis


Abstract

Human herpesvirus 8 (HHV‐8) is detected more often in patients progressing towards Kaposi's sarcoma (KS) than in patients who do not develop the disease, suggesting that the level of viremia might be associated with Kaposi's sarcoma disease and progression. Longitudinal serum samples from 19 AIDS‐Kaposi's sarcoma patients, ranging from 2 years before KS till 2 years after KS diagnosis were tested. No correlation was found between viral load and progression to KS, or disease stage. J. Med. Virol. 74:390–396, 2004. © 2004 Wiley‐Liss, Inc.