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Retrospective exposure assessment with emission inventories: a new approach to an old problem

✍ Scribed by James Argo

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
180 KB
Volume
9
Category
Article
ISSN
1180-4009

No coin nor oath required. For personal study only.

✦ Synopsis

A procedure to estimate chemical exposure retrospectively for the purpose of studying individual chronic chemical exposure is described. We use the unique combination of a case-control study design which eliminates dilution by mobility, coupled with an emission inventory to estimate exposure nationally for up to 35 years latency. The retrospective exposure assessment (REA) methodology leads to an Exposure Index (EI) to describe the average historic exposure at a point. The approach is demonstrated with an estimate of the average chemical environment in each of 78 pulp producing communities in Canada in 1980 considering process-related emissions. A procedure to partially validate the pollution estimate and the estimate of toxicity is shown.

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