Retrospective analysis of drug treatment in epileptic patients
β Scribed by Rwiza, H. T. ;Keyser, A. ;Hekster, Y. A. ;Pool, M. ;Verwey, H.
- Publisher
- Springer
- Year
- 1989
- Tongue
- Dutch
- Weight
- 648 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1573-739X
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In order to evaluate the influence of chronic antiepileptic drug treatment on the kinetics of the antidepressant viloxazine (VLX), six drug-free control subjects and six epileptic patients treated with one or two anticonvulsants (phenobarbital, carbamazepine or phenytoin) were given a single oral do
## Abstract Six severe epileptic patients developed stuporous encephalopathy with marked cognitive impairment when topiramate (TPM) and sodium valproate (VPA) were coprescribed for five patients, and when monotherapy with TPM was introduced for one patient. In four patients, ammonaemia increased an