Retroperitoneal sarcomas (RPS) are rare tumors, accounting for approximately 15% of soft tissue sarcomas. Surgical resection of localized tumors with gross and microscopically negative margins remains the standard of care. However, because RPS are frequently large and locally advanced, resections ar
Retroperitoneal sarcomas: A reappraisal of treatment
β Scribed by F. Kristian Storm; Frederick R. Eilber; Joseph Mirra; Donald L. Morton
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 393 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0022-4790
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Retroperitoneal sarcoma, regardless of the histopathologic grade of malignancy, has a high incidence of local recurrence that is usually fatal. Surgical resection is mandatory and resectability may be improved by a midline transabdominal approach. However, even with total tumor excision, recurrence is high. A preliminary study, combining resection and preoperative adriamycin, found to be effective for established disease, suggests potentially improved prognosis. Further clinical trials employing surgery combined with adjuvant chemotherapy are warranted.
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