Retroperitoneal neuroblastoma widely metastatic to the central nervous system
β Scribed by Dr Steven Dresler; Danny G. Harvey; Paul M. Levisohn
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 398 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
A girl with congenital extraadrenal neuroblastoma died at 3 months of age with multiple parenchymal metastases in the brain and spinal cord. The bones of the skull, cranial dura, venous sinuses, and orbits were not involved. Autopsy findings suggest that the tumor penetrated the spinal meninges and disseminated through the cerebrospinal fluid. It is possible that hematogenous metastasis occurred as well. The intracerebral metastases were not identified on a CT scan performed several hours before the child's death.
π SIMILAR VOLUMES
T he diagnosis of a central nervous system (CNS) lesion as a neo- plasm often precipitates a treatment plan that includes radiation and chemotherapy. Although these modalities are effective for some CNS tumors, they also have well known side effects that are prone to appear during the long postopera
Childhood neuroblastoma is a neural crest-derived tumor that presents most commonly during this period of life. In disseminated form, it is resistant to cure by chemotherapy. The tumor tends to recur in diverse locations after an initial clinical response. The parenchyma of the central nervous syste