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Retromolar trigone squamous cell carcinoma treated with radiotherapy alone or combined with surgery

✍ Scribed by William M. Mendenhall; Christopher G. Morris; Robert J. Amdur; John W. Werning; Douglas B. Villaret

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
73 KB
Volume
103
Category
Article
ISSN
0008-543X

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✦ Synopsis

Abstract

BACKGROUND

Treatment outcomes were analyzed for retromolar trigone squamous cell carcinoma.

METHODS

Between June 1966 and August 2003, 99 patients were treated with radiotherapy alone (35 patients) or radiotherapy combined with surgery (64 patients). Followup ranged from 0.2 to 23.8 years (median, 3.3 yrs). All living patients had followup for at least 1 year.

RESULTS

The 5‐year local–regional control rates after definitive radiotherapy versus surgery and radiotherapy were as follows: Stages I–III, 51% and 87%; Stage IV, 42% and 62%; and overall, 48% and 71%, respectively. The 5‐year cause‐specific survival rates after definitive radiotherapy compared with surgery and radiotherapy were as follows: Stages I–III, 56% and 83%; Stage IV, 50% and 61%; and overall, 52% and 69%, respectively. Multivariate analyses revealed that the likelihood of cure was better with surgery and radiotherapy compared with definitive radiotherapy.

CONCLUSIONS

The likelihood of cure after treatment for retromolar trigone squamous cell carcinoma was influenced by the extent of disease and treatment. Patients treated with surgery and radiotherapy had a better outcome than those treated with radiotherapy alone. Cancer 2005. Β© 2005 American Cancer Society.

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