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RET/PCM-1: a novel fusion gene in papillary thyroid carcinoma

✍ Scribed by Berger, N; Balczon, R; Romeo, G; Corvi, R

Book ID
110064091
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
374 KB
Volume
19
Category
Article
ISSN
0950-9232

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Fusion of a novel gene, ELKS, to RET due
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In papillary thyroid carcinomas, the genes for receptor-type tyrosine kinase, RET or TRKA, are sometimes rearranged, resulting in fusion of its tyrosine kinase domain to 5Ј portions of several activating genes. In a papillary thyroid carcinoma, we identified a novel gene (ELKS), the 5Ј portion of wh