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Retinole acid and glucocorticoids enhance the effect of 1,25-dihydroxyvitamin D3 on bone γ-carboxyglutamic acid protein synthesis by rat osteosarcoma cells

✍ Scribed by Satoru K. Nishimoto; Carl Salka; Marcel E. Nimni


Book ID
112118292
Publisher
American Society for Bone and Mineral Research
Year
2009
Tongue
English
Weight
549 KB
Volume
2
Category
Article
ISSN
0884-0431

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Our laboratory has recently demonstrated that 1,25-dihydroxyvitamin D,(1,25(OH),D3) rapidly stimulated membrane polyphosphoinositide breakdown and increased intracellular calcium, as well as activated protein kinase C (PKC) in vitamin D-sufficient rat colonocytes. These effects of 1,25(OH),D, were,