Fluorescent retinoid X receptor ligands
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Shoya Yamada; Fuminori Ohsawa; Shuji Fujii; Ryosuke Shinozaki; Makoto Makishima;
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Article
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2010
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Elsevier Science
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English
β 538 KB
Retinoid X receptor (RXR) agonists are candidate agents for the treatment of metabolic syndrome and type 2 diabetes via activation of peroxisome proliferator-activated receptor (PPAR)/RXR or liver X receptor (LXR)/RXR-heterodimers, which control lipid and glucose metabolism. Reporter gene assays or