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Retinoid status and responsiveness to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking retinoid binding protein or retinoid receptor forms

✍ Scribed by Pi Hoegberg; Carsten K. Schmidt; Nick Fletcher; Charlotte B. Nilsson; Christina Trossvik; A. Gerlienke Schuur; Abraham Brouwer; Heinz Nau; Norbert B. Ghyselinck; Pierre Chambon; Helen Håkansson


Book ID
113517184
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
209 KB
Volume
156
Category
Article
ISSN
0009-2797

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Oral doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) were administered twice within 7 d (total concentration 0.01, 0.1, 1, 10, or 100 g TCDD/kg body weight) to flounder (Platichthys flesus). After 10 d of exposure, flounder were sacrificed, and the effects of TCDD exposure on hepatic microsomal