Retinoic acid up-regulates the expression of major histocompatibility complex molecules and adhesion/costimulation molecules (specifically, intercellular adhesion molecule ICAM-1) in human cervical cancer
โ Scribed by Alessandro D. Santin; Paul L. Hermonat; Antonella Ravaggi; Maurizio Chiriva-Internati; Sergio Pecorelli; Groesbeck P. Parham
- Book ID
- 113985514
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 142 KB
- Volume
- 179
- Category
- Article
- ISSN
- 1097-6868
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Tumor cells from 7 freshly isolated human ovarian tumors and 2 continuous human ovarian cancer cell lines were analyzed for their surface expression of MHC class-I, class-ll and ICAM-I surface antigens before and after exposure to y-irradiation and/or the cytokines TNF-a plus IFN-y. All 7 fresh tumo