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Retinoic acid repressed the expression of c-fos and c-jun and induced apoptosis in regenerating rat liver after partial hepatectomy

โœ Scribed by Ayumi Ozeki; Ikuyo Tsukamoto

Book ID
117351156
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
469 KB
Volume
1450
Category
Article
ISSN
0167-4889

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Chronic ethanol intake may interfere with retinoid signal transduction by inhibiting retinoic acid synthesis and by enhancing activator protein-1 (AP-1) (c-Jun and c-Fos) expression, thereby contributing to malignant transformation. To determine the effect of ethanol on hepatic retinoid levels, reti