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Retinoic Acid Regulates, in vitro, the Two Normal Pathways of Differentiation of Human Laryngeal Keratinocytes

✍ Scribed by Michael G. Mendelsohn, Teresa P. Dilorenzo, Allan L. Abramson and Bettie M. Steinberg


Book ID
125622888
Publisher
Society for In Vitro Biology
Year
1991
Tongue
English
Weight
705 KB
Volume
27A
Category
Article
ISSN
1475-2689

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1,25-Dihydroxyvitamin D 3 [1,25(OH) 2 D 3 ] and all-trans retinoic acid (RA), the active metabolites of vitamins D and A respectively, regulate the proliferation and differentiation of keratinocytes. Both the vitamin D receptor (VDR) and the retinoic acid receptor family (RAR) bind to DNA response e