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Retinoic Acid Receptor α in Acute Promyelocytic Leukemia

✍ Scribed by C. LAVAU; H. DE THÉ; A. DEJEAN


Book ID
119868975
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
491 KB
Volume
684
Category
Article
ISSN
0890-6564

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Treatment of the acute promyelocytic (APL) cell line NB4 with interferon alpha (IFN(alpha)), as well as IFN(beta) and gamma, results in an increased expression of the transcripts coding for retinoic-acid receptor type alpha (RAR(alpha)) and the leukemia-specific retinoic acid receptor PML-RAR. Trans