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Retinoic acid receptor antagonist BMS453 inhibits the growth of normal and malignant breast cells without activating RAR–dependent gene expression

✍ Scribed by L. Yang; D. Munoz–Medellin; H-T. Kim; J. Ostrowski; P. Reczek; P.H. Brown


Book ID
110233225
Publisher
Springer US
Year
1999
Tongue
English
Weight
190 KB
Volume
56
Category
Article
ISSN
0167-6806

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Estrogen receptor-negative breast cancer
✍ M. Saeed Sheikh; Zhi-Ming Shao; Jian-Chyi Chen; Arif Hussain; Anton M. Jetten; J 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 968 KB

We and others have shown previously that retinoic acid (RA) selectively inhibits the growth of estrogen receptor (ER)-positive human breast carcinoma (HBC) cells and ER-negative cells are refractory to RA inhibition o f growth. The ER-negative cells inherently express lower levels of RARa and retino