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Retinoic acid prevents accumulation of a mesoderm-specific mRNA in the amphibian embryo

โœ Scribed by Brennan, Sean M.

Book ID
123211281
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
901 KB
Volume
38
Category
Article
ISSN
0925-4773

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Several differentiation-specific genes, including those for collagen IV and laminin, are induced by retinoic acid IRA) in mouse F9 teratocarcinoma cells. Dibutyryl CAMP can enhance the effect of RA in these cells, but dibutyryl CAMP alone does not induce these genes. Inhibition of RNA synthesis with