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Retinoic acid inhibits phospholipid turnover and protein kinase C activity in RA-sensitive but not in RA-resistant cells

✍ Scribed by M.C. Vanier; D. Banerjee; B.B. Mukherjee


Book ID
115921157
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
294 KB
Volume
241
Category
Article
ISSN
0014-5793

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## Abstract All‐trans retinoic acid (ATRA), a synthetic derivative of vitamin A, inhibits the growth of breast cancer cells. To elucidate the mechanism by which ATRA causes cell growth inhibition, we examined changes in cell cycle and intracellular signaling pathways, focusing on protein kinase C (