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Retinoic acid induces REST degradation and neuronal differentiation by modulating the expression of SCFβ-TRCP in neuroblastoma cells

✍ Scribed by Akanksha Singh; Christopher Rokes; Monica Gireud; Stephen Fletcher; James Baumgartner; Greg Fuller; John Stewart; Peter Zage; Vidya Gopalakrishnan

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
820 KB
Volume
117
Category
Article
ISSN
0008-543X

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## Abstract In this article, we selectively extracted the nuclear matrix and intermediate filament system of human neuroblastoma SK‐N‐SH cells pre‐ and post‐treated with retinoic acid (RA). The distribution of nucleophosmin (NPM) in the nuclear matrix and its colocalization with several products of