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Retinoic Acid Induces Rapid Mineralization and Expression of Mineralization-Related Genes in Chondrocytes

โœ Scribed by Masahiro Iwamoto; Irving M. Shapiro; Kimitoshi Yagami; Adele L. Boskey; Phoebe S. Leboy; Sherrill L. Adams; Maurizio Pacifici

Book ID
115601527
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
745 KB
Volume
207
Category
Article
ISSN
0014-4827

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Transcriptional suppression of Sox9 expr
Transcriptional suppression of Sox9 expression in chondrocytes by retinoic acid
โœ Ichiro Sekiya; Peter Koopman; Kunikazu Tsuji; Sabine Mertin; Vincent Harley; Yos ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 168 KB

SOX9 is a transcription factor that is expressed in chondrocytes and regulates expression of chondrocyte phenotype related genes. Expression of these genes is known to be suppressed by retinoic acid (RA). We, therefore, examined whether the Sox9 gene expression is regulated by RA in chondrocytes. RA