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Retinoic Acid Induces MAP-2-Containing Neurites in Mouse Neuroblastoma Cells

✍ Scribed by ITZHAK FISCHER; THOMAS B. SHEA; KENNETH S. KOSIK; VICTOR S. SAPIRSTEIN

Book ID
118723901
Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
149 KB
Volume
466
Category
Article
ISSN
0890-6564

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## Abstract Neuroblastoma, the most common extracranial solid tumor in children, arises from precursors of the sympathetic nervous system. Neuroblastoma cell lines are responsive to the differentiation agent retinoic acid, which induces its effects by altering transcription rates of specific target