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Retinoic Acid-Induced blr1 Expression Promotes ERK2 Activation and Cell Differentiation in HL-60 Cells

✍ Scribed by Traci E. Battle; Roy A. Levine; Andrew Yen

Book ID: 115603568
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 257 KB
Volume: 254
Category: Article
ISSN: 0014-4827
DOI: 10.1006/excr.1999.4766

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## Abstract Retinoic acid‐induced expression of the CD38 ectoenzyme receptor in HL‐60 human myeloblastic leukemia cells is regulated by RARα and RXR, and enhanced or prevented cell differentiation depending on the level of expression per cell. RARα activation caused CD38 expression, as did RXR acti