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Retinoic acid enhances the secretion of plasminogen from cultured rat microglia

โœ Scribed by Kazuyuki Nakajima; Nagisa Takemoto; Shinichi Kohsaka


Book ID
115926643
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
272 KB
Volume
314
Category
Article
ISSN
0014-5793

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โœ Beomsue Kim; Jee-Hyung Lee; Myung-Soon Yang; Ilo Jou; Eun-Hye Joe ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 403 KB

Retinoic acid (RA) is a well-known antiinflammatory agent. In this study, we show that RA has a dual effect on cyclooxygenase-2 (COX-2) expression in inflammatory activated microglia, the resident brain macrophages. After treatment of microglia with LPS or thrombin, COX-2 expression was induced in t