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Retinoblastoma Protein Phosphorylation via PI 3-Kinase and mTOR Pathway Regulates Adipocyte Differentiation

โœ Scribed by Isao Usui; Tetsuro Haruta; Minoru Iwata; Atsuko Takano; Tatsuhito Uno; Junko Kawahara; Eiichi Ueno; Toshiyasu Sasaoka; Masashi Kobayashi


Book ID
115586282
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
134 KB
Volume
275
Category
Article
ISSN
0006-291X

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## Abstract We previously showed that prolonged and strong ERK phosphorylation induced by Compound 5 (Cpd 5), a Cdc25A protein phosphatase inhibitor, was involved in its mechanism of cell growth inhibition. To study the relationship between ERK phosphorylation and cell growth inhibition, we used Cp