Alterations of expression of Rb, p16INK4
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Brambilla, Elisabeth; Moro, Denis; Gazzeri, Sylvie; Brambilla, Christian
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Article
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1999
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John Wiley and Sons
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English
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## Inactivation of the Rb pathway in non-small cell lung carcinoma (NSCLC) occurs mostly through inactivation of the cyclin-dependent kinase inhibitor p16 INK4A and/or up-regulation of cyclin D1. In order to assess the frequency and the prognostic value of these abnormalities in NSCLC, immunohisto