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Retinal Pathology and Function in a Cln3 Knockout Mouse Model of Juvenile Neuronal Ceroid Lipofuscinosis (Batten Disease)

โœ Scribed by Gail M. Seigel; Andrew Lotery; Ari Kummer; David J. Bernard; Nicholas D.E. Greene; Mark Turmaine; Todd Derksen; Robert L. Nussbaum; Beverly Davidson; Janet Wagner; Hannah M. Mitchison


Book ID
115637840
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
954 KB
Volume
19
Category
Article
ISSN
1044-7431

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The human hereditary ceroid-lipofuscinoses are a group of autosomal recessively inherited diseases characterized by massive accumulations of autofluorescent lysosomal storage bodies in the cells of many tissues and by neuronal degeneration throughout the central nervous system. There are a number of