Retinal oscillatory potential abnormalities in patients with chronic renal failure, before and after dialytic treatment
✍ Scribed by A. Polo; L. Lazzarino; F. Pitzorno; E. Beltram; G. Zanette; D. Grandis
- Publisher
- Springer-Verlag
- Year
- 1992
- Tongue
- English
- Weight
- 387 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0012-4486
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✦ Synopsis
Nineteen patients with chronic renal failure were studied, oscillatory potentials (OPs) being recorded shortly before and after dialytic treatment. Mean values of either onset latency (O1 latency) and duration of the complex (O1-N4 inter-peak latency) were found to be significantly longer in patients than in controls (p < 0.001). Most of the patients (12) showed a pathological prolongation of latency (>2.5 SD). Amplitude changes also affected OPs, but earlier components were reduced to a lesser degree than the later ones, as shown by statistical analysis. Moreover, seven patients showed an almost complete loss of 03 and 04 peaks. Latency changes may be transiently reversed by dialysis, suggesting a functional impairment of the retinal response; the loss of later components is a more persistent abnormality probably related with a structural damage.