Retention of Zinc-65 in the Bones of Rats
β Scribed by TAYLOR, D. M.
- Book ID
- 109614491
- Publisher
- Nature Publishing Group
- Year
- 1961
- Tongue
- English
- Weight
- 196 KB
- Volume
- 189
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/189932a0
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The effects of tetracycline on the absorption of orally ingested 65Zn was studied on rats by whole body counting assay. 65Zn was given as a single dose to groups of rats, five in each, which were started on tetracycline. Tetracycline was given in daily doses of 25 mg, 50 mg, 100 mg, and 200 mg for 1
Seven groups of 8 rats each were orally loaded with zinc, the daily dose varying from 1.8 to 58 mg, corresponding to about 3 to 100 times of their estimated daily intake of zinc. To record the absorption of zinc, the rats were given a single dose of 65Zn. The retention of the isotope was measured in