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RET genotypes in sporadic medullary thyroid cancer: studies in a large Italian series

✍ Scribed by Laura Fugazzola; Marina Muzza; Caterina Mian; Daniela Cordella; Susi Barollo; Luisella Alberti; Valentina Cirello; Davide Dazzi; Maria Elisa Girelli; Giuseppe Opocher; Paolo Beck-Peccoz; Luca Persani

Book ID
108704097
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
291 KB
Volume
69
Category
Article
ISSN
0300-0664

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πŸ“œ SIMILAR VOLUMES

Mutation of the RET protooncogene in spo
Mutation of the RET protooncogene in sporadic medullary thyroid carcinoma
✍ Charis Eng; Lois M. Mulligan; Darrin P. Smith; Catherine S. Healey; Andrea Frill πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 375 KB

Medullary thyroid carcinoma (MTC) occurs sporadically or as part of the inherited cancer syndrome multiple endocrine neoplasia (MEN) type 2. In MEN 2A, germline missense mutations are found in one of five cysteine codons within exons 10 and I I in the extracellular domain of the RET protooncogene. I