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Resveratrol inhibits the mevalonate pathway and potentiates the antiproliferative effects of simvastatin in rat theca-interstitial cells

✍ Scribed by Donna H. Wong; Jesus A. Villanueva; Amanda B. Cress; Anna Sokalska; Israel Ortega; Antoni J. Duleba

Book ID: 116479991
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 311 KB
Volume: 96
Category: Article
ISSN: 1556-5653
DOI: 10.1016/j.fertnstert.2011.08.010

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## Abstract Excitotoxicity and cell death induced by glutamate are involved in many neurodegenerative disorders. We have previously demonstrated that excitotoxicity induced by millimolar concentrations of glutamate in hippocampal slices involves apoptotic features and glutamate‐induced glutamate re