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Resveratrol-induced G2 arrest through the inhibition of CDK7 and p34CDC2 kinases in colon carcinoma HT29 cells

โœ Scribed by Yu-Chih Liang; Shu-Huei Tsai; Linda Chen; Shoei-Yn Lin-Shiau; Jen-Kun Lin


Book ID
113993421
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
345 KB
Volume
65
Category
Article
ISSN
0006-2952

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## Abstract Abnormalities in cell cycle progression provide unlimited replicative potential to cancer cells, and therefore targeting of key cell cycle regulators could be a sound cancer chemopreventive strategy. Earlier, we found that grape seed extract (GSE) increases Cip/p21 protein level and inh