Resveratrol analog trans 3,4,5,4′-tetramethoxystilbene (DMU-212) mediates anti-tumor effects via mechanism different from that of resveratrol

Comparison of the effects of the chemopr

Comparison of the effects of the chemopreventive agent resveratrol and its synthetic analog trans 3,4,5,4′-tetramethoxystilbene (DMU-212) on adenoma development in the ApcMin+ mouse and cyclooxygenase-2 in human-derived colon cancer cells

✍ Stewart Sale; Richard G. Tunstall; Ketan C. Ruparelia; Gerry A. Potter; William 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 306 KB 👁 1 views

## Abstract Naturally occurring molecules with putative cancer chemopreventive properties such as the phytoalexin resveratrol (3,5,4′‐trihydroxystilbene) are lead molecules that guide the design of novel agents with improved pharmacologic properties. The synthetic resveratrol analog 3,4,5,4′‐tetram