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Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: Role of nitric oxide, thioredoxin, and heme oxygenase

✍ Scribed by Mahesh Thirunavukkarasu; Suresh Varma Penumathsa; Srikanth Koneru; Bela Juhasz; Lijun Zhan; Hajime Otani; Debasis Bagchi; Dipak K. Das; Nilanjana Maulik

Book ID: 113630339
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 746 KB
Volume: 43
Category: Article
ISSN: 0891-5849
DOI: 10.1016/j.freeradbiomed.2007.05.004

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## Abstract Chronic exposure of pancreatic β‐cells to supraphysiologic glucose causes adverse β‐cell dysfunction. Thus, the present study was aimed to investigate the hypothesis that oral administration of resveratrol attenuates hyperglycemia, proinflammatory cytokines and antioxidant competence an