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Results of phase II and phase III trials with new aromatase inhibitors

โœ Scribed by W. Jonat


Book ID
114316809
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
864 KB
Volume
5
Category
Article
ISSN
0960-9776

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CGS 16949A is a new, nonsteroidal competitive inhibitor of the aromatase enzyme. In this Phase I trial, 16 heavily pretreated postmenopausal patients with metastatic breast cancer were treated with escalating doses of CGS 16949A from 0.6 to 16 mg total daily oral dose. No hematologic, biochemical, o