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Results of decitabine therapy in the accelerated and blastic phases of chronic myelogenous leukemia

✍ Scribed by Kantarjian, H M; O’Brien, S M; Keating, M; Beran, M; Estey, E; Giralt, S; Kornblau, S; Rios, M B; de Vos, D; Talpaz, M

Book ID
110053637
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
197 KB
Volume
11
Category
Article
ISSN
0887-6924

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## Abstract ## BACKGROUND General and site‐specific DNA methylation is associated with tumor progression and resistance in several cancers, including chronic myelogenous leukemia (CML). Decitabine is a hypomethylating agent that has shown encouraging preliminary anti‐CML activity. This study evalu