Results of a screening program for c-cell disease (medullary thyroid cancer and c-cell hyperplasia)
β Scribed by W. John Simpson; John S. Carruthers; Dina Malkin
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 659 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0008-543X
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π SIMILAR VOLUMES
Four years following resection of a medullary carcinoma of the thyroid, a 49-year-old man experienced elevated serum calcitonin levels. There was no evidence of metastasis. A re-exploration of the patient's neck demonstrated a histologically normal thyroid remnant that demonstrated C-cell hyperplasi
Background. The diagnosis of medullary thyroid carcinoma (MTC) depends on the calcitonin immunohistochemistry. Familial MTC is associated with C-cell hyperplasia (CCH), whereas sporadic MTC is not. A specific and sensitive calcitonin immunohistochemistry is necessary for the diagnosis of MTC and CCH