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Restriction-PCR fingerprinting of the immunoglobulin VH repertoire: direct detection of an immune response and global analysis of B cell clonality

✍ Scribed by Harry N. White

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
182 KB
Volume
28
Category
Article
ISSN
0014-2980

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A study was performed to investigate the utility of polymerase chain reaction (PCR)-based analysis of immunoglobulin heavy chain (IgH) gene rearrangements for the diagnosis of low-grade malignant B-cell lymphomas on formalin-®xed, EDTA-decalci®ed, and paraf®n-embedded bone marrow trephine biopsies.