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Restriction fragment length polymorphisms detected by anonymous DNA probes mapped to defined intervals of human chromosome 16

✍ Scribed by V. J. Hyland; S. Grist; G. R. Sutherland

Publisher: Springer
Year: 1988
Tongue: English
Weight: 534 KB
Volume: 79
Category: Article
ISSN: 0340-6717
DOI: 10.1007/bf00366251

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✦ Synopsis

Three anonymous DNA probes ACH207, ACH224, and ACH202, isolated from a flow-purified chromosome 16 library and mapped to defined intervals of human chromosome 16, detected restriction fragment length polymorphisms (RFLPs). The RFLPs were of simple two allele types. The ACH207 (D16S4) probe detected a TaqI and an MspI RFLP with polymorphism information content (PIC) values of 0.30 and 0.27; the ACH224 (D16S5) probe detected an RsaI RFLP, PIC value of 0.34; and the ACH202 (D16S14) probe detected an XbaI RFLP, PIC value of 0.22.

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