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Restriction Fragment Length Polymorphism Analysis in Healthy Japanese Individuals and Japanese Families with Gaucher Disease

โœ Scribed by Mitsuo Masuno; Tadao Orii; Kazuko Sukegawa; Toshiaki Taga


Book ID
118711358
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
645 KB
Volume
31
Category
Article
ISSN
1328-8067

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Deficiency in hepatic tyrosine aminotransferase (TAT) causes tyrosinemia type II, an autosomal recessively inherited disorder. Using a TAT cosmid clone, we have identified an MspI restriction fragment length polymorphism (RFLP) 5' to the TAT gene, with allele frequencies of 0.63 and 0.37. Analysis o